Salvage of locoregionally recurrent head and neck cancer: an NRG oncology working group review
Year: 2026
Type: article
Abstract: Despite decades of progress in the treatment of head and neck cancer, recurrence and second primary cancers continue to occur. The management of nonmetastatic, locoregionally recurrent or second primary cancers is a complex multidisciplinary challenge that often occurs without guidance from robust clinical trials. In 2023, the NRG Oncology cooperative group created the Recurrent and Metastatic Working Group with the express directive to investigate how resources could optimally address the key questions for the recurrent and metastatic populations. Here, we present our view of the state of the science and present considerations for future investigations.
DOI: 10.1093/jnci/djag025
Institutions: Levine Cancer Institute, Southeast Radiation Oncology Group, Yale University, Emory University, Winship Cancer Institute, Cleveland Clinic, The University of Texas MD Anderson Cancer Center, Henry Ford Health, Henry Ford Hospital, University of Alabama at Birmingham, University Health Network, Princess Margaret Cancer Centre, Harvard University, Dana-Farber Cancer Institute, University of California, San Francisco, Bon Secours Mercy Health
Language: English
Topic: Head and Neck Cancer Studies
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: National Cancer Institute
OpenAlex ID: W7127456301