Umbilical cord plasma markers in gestational diabetes: evidence of fetal metaflammation, elevated GGT, and links to neonatal metabolic health
Year: 2026
Type: article
Study design: Observational Study
Abstract: Excess fetal nutrient supply in gestational diabetes mellitus (GDM) results in signs of fetal metabolic inflammation (metaflammation) in umbilical cord plasma, and higher levels of γ-glutamyl transferase (GGT), a liver enzyme involved in defense against oxidative stress. The correlations of GGT levels with reduced insulin resistance, C-peptide, and leptin suggest that GGT has a positive effect on fetal metabolic health.
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Awards: Neprilysin in Pregnancy, G993000222
OpenAlex ID: W7127566587