Work

CXCR4 inhibition alleviates prostatic inflammation and pelvic pain via suppressing Th17 cell differentiation and oxidative stress in EAP mice

Year: 2026

Type: article

Abstract: CXCR4 presents a promising therapeutic target for CP/CPPS. Pharmacological blockade of CXCR4 with AMD3100 inhibits Th17 cell differentiation, consequently mitigating inflammatory infiltration and oxidative tissue injury in CP/CPPS.

Source: International Journal of Biological Sciences

DOI: 10.7150/ijbs.124532

Authors: Yongtao Hu, Yi Liu, Jialin Meng, Ruijie Hu, Wenming Ma, Wenlong Xu, Kun Tang, Xianchao Dou, Chaozhao Liang, Li Zhang, Jing Chen

Institutions: Anhui Medical University, First Affiliated Hospital of Anhui Medical University

Language: English

Topic: Urinary Bladder and Prostate Research

Subfield: Urology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,337

OpenAlex ID: W7127570371

FWCI: 35.58

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Cited by: 5

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