Factors contributing to medication non-adherence in a hypertensive Saudi population: a literature review
Year: 2025
Type: article
Study design: Systematic Review
Abstract: Hypertension is a leading non-communicable disease both globally and in Saudi Arabia. Poor adherence to antihypertensive medications remains a major challenge in managing this condition, contributing to higher morbidity, mortality, and healthcare costs. This study aimed to review and synthesize the literature on factors contributing to medication nonadherence among hypertensive patients in Saudi Arabia. A structured literature review was conducted using the PubMed and Scopus databases. Inclusion criteria include English-language studies conducted in Saudi Arabia from 2010 to 2024 involving hypertensive adult Saudi patients. A total of 84 studies were identified. Eleven studies met the final inclusion criteria. All were cross-sectional studies using different validated adherence assessment tools. Adherence rates varied widely, from 33% to 86.1%, influenced by the choice of measurement tool and regional differences. Higher adherence was associated with older age, female gender, higher education level, being married, and higher income. Psychosocial and behavioral factors, including beliefs about the necessity of medication, perceived social support, and strong physician-patient relationships, positively influenced adherence. One study using the Health Belief Model (HBM) found that perceived severity, susceptibility, benefits, and cues to action significantly affected adherence behaviors. Medication adherence among hypertensive patients in the Saudi population is influenced by a complex relationship of demographic, psychosocial, and healthcare-related factors. Addressing these elements through tailored interventions and appropriate assessment tools may enhance hypertension management outcomes.
Source: Journal of Medicine and Life
Institutions: King Fahd Military Medical Complex, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Imam Abdulrahman Al Faisal Hospital, National Guard Health Affairs, Almaarefa University, Riyadh Armed Forces Hospital, Jazan University, King Saud University
Language: English
Subfield: Family Practice
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7127571202
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