Chimeric antigen receptor T cells against the IGHV4-34 B cell receptor specifically eliminate neoplastic and autoimmune B cells
Year: 2026
Type: article
Source: Science Translational Medicine
Authors: Ivan J. Cohen, Audrey C. Bochi-Layec, Jean Lemoine, Scott Jenks, Pedram Bayat, Ki Hyun Kim, Huiwu Zhao, Ositadimma Ugwuanyi, Federico Stella, Guido Ghilardi, Giulia Gabrielli, Sarah McCuaig, Anastasia Iatrou, Elisavet Vlachonikola, Maria Karipidou, Eleni Bouziani, David Espie, Ranjani Ramasubramanian, Andreas Agathangelidis, Aditya Bhosale, Luca Paruzzo, Giovanni Medico, Bronte Kolar, Regina Bugrovsky, Puneeth Guruprasad, Li-Ping Wang, Jaryse Harris, Evgeny Arons, Yunlin Zhang, Raymone Pajarillo, Portia A. Kreiger, Chi-Ping Day, S. Cenk Sahinalp, Chih Hao Wu, Alessia Santi, Bria Fulmer, Marcos Cases, Matthew B. Palmer, Patrizia Porazzi, E. John Wherry, Robert J. Kreitman, Enrico Tiacci, Sokratis A. Apostolidis, Edward M. Behrens, Vijay Bhoj, Ignacio Sanz, Giorgio Inghirami, Stephen J. Schuster, Paolo Ghia, Kostas Stamatopoulos, Marco Ruella
Institutions: Hospital of the University of Pennsylvania, Abramson Cancer Center, University of Pennsylvania, Emory University, Children's Hospital of Philadelphia, Centre for Research and Technology Hellas, National and Kapodistrian University of Athens, NewYork–Presbyterian Hospital, Weill Cornell Medicine, National Institutes of Health, National Cancer Institute, Center for Cancer Research, University of Perugia, Azienda Ospedaliera di Perugia, Vita-Salute San Raffaele University, IRCCS Ospedale San Raffaele
Language: English
Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: closed
Funders: Center for High Performance Computing, Shanghai Jiao Tong University, Lymphoma Research Foundation, Hairy Cell Leukemia Research Foundation, Leukemia and Lymphoma Society, Frederick National Laboratory for Cancer Research, Associazione Italiana per la Ricerca sul Cancro, Colton Foundation, DKMS Foundation
Awards: G2132873222, G2406870047
OpenAlex ID: W7127590696