Work

Antimicrobial performance of amorphous vs. crystalline La1-xSrxCoO3 perovskites

Year: 2026

Type: article

Abstract: Perovskite materials, with their unique crystal structure and chemical properties, are emerging as promising antimicrobial agents for potential biomedical applications. In this research, different weight percentages of Sr 2 + doped amorphous and crystalline Lanthanum Cobaltite (La 1-x Sr x CoO 3 defined as LSCO) (x = 0, 0.025, 0.05, 0.1, and 0.15) perovskite was synthesized by using a simple combination of sol-gel and molten-salt processes and characterized by X-ray diffraction (XRD), and scanning electron microscopy (SEM) ensures the uniform morphology of the materials. During antimicrobial study using the Kirby Bauer method, amorphous LSCO showed much better activity than crystalline LSCO against Escherichia coli , Vibrio cholerae , and Bacillus subtilis species. Particularly, the 5 % Sr 2+ doped LSCO showed the best performance against Vibrio cholerae, with a 10.44 % increase in the inhibition zone when compared to the undoped LSCO . Furthermore, the 2.5 % Sr 2+ doped LSCO increased the inhibition zone by 14.03 % against Escherichia coli. However, it is interesting to note that the introduction of doping resulted in a decline in antibacterial effectiveness for Bacillus subtilis . Ultimately, the largest inhibition zone of 54.5 ± 1.8 mm was recorded against Vibrio cholerae , specifically for La 0.95 Sr 0.05 CoO 3 . These findings clearly highlight the significant impact of Sr²⁺ doping on the antimicrobial properties of LSCO, demonstrating its potential as a valuable material for antibacterial applications. • Perovskites are promising antimicrobial nanomaterials. • Sr²⁺ doped amorphous and crystalline LSCO were developed. • Amorphous LSCO showed superior antimicrobial activity. • La₀.₉₅Sr₀.₀₅CoO₃ reached a 54.50 mm inhibition zone. • Sr²⁺ doping significantly enhanced antibacterial behavior.

Source: Next Materials

DOI: 10.1016/j.nxmate.2026.101688

Authors: SM Anyet Ullah Shohag, Fahmida Akhter, Ahmed Touhami, Swati Mohan, Md. Wasikur Rahman, M. Jasim Uddin

Institutions: The University of Texas at Dallas, The University of Texas Rio Grande Valley, Jagannath University, SUNY Polytechnic Institute

Language: English

Topic: Nanoparticles: synthesis and applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,280