Year: 2025
Type: review
Abstract: Background Exercise has great potential for enhancing brain health and preventing or treating neurological conditions. Three molecular pathways have been identified: neuroprotection, neurotrophic factor increase, and neurotransmitter modulation. Methodology We reviewed PubMed, Scopus, and Google Scholar according to PRISMA criteria. The inclusion criteria included studies with peer review providing molecular insights into the effects of exercise on brain function. Results Through neurotrophic factors, neurotransmitter modulation, mitochondrial biogenesis, and neuroprotection, exercise benefits brain function. These modifications are correlated with better mood management, enhanced cognitive function, and the prevention of neurodegenerative diseases. Conclusion The various benefits of exercise on neurological disorders and brain health are highlighted in this study, with particular attention to key molecular pathways. Exercise is a vital tool in the management of neurological health.
Language: English
Topic: Physical Activity and Health
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7127645611