Work

Myocardial Infarction, Stroke, and Death after Intravitreal Injection of Anti-VEGF in a Nationwide Study

Year: 2026

Type: article

Abstract: Objective: To assess the risk of myocardial infarction, stroke, and death after intravitreal injection (IVT) of anti-vascular endothelial growth factor (VEGF) on a national scale. Design: A controlled cohort study from 2010 to 2016 in France. Subjects Participants and Controls: Patients receiving an anti-VEGF IVT or undergoing cataract surgery. Main Outcome Measures: Occurrence of myocardial infarction, stroke, or death. Results: = 0.10). Conclusions: The overall risk of the main outcome was low after 1 IVT. In the stratified analysis of aflibercept and ranibizumab IVT, no difference was found in the risk for the main outcome between the 2 agents. Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Source: Ophthalmology Science

DOI: 10.1016/j.xops.2026.101104