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Additional file 5 of Calcineurin depletion coincides with phosphorylated TDP-43 deposition in a mouse model of ALS/FTLD-TDP

Year: 2026

Type: other

Abstract: Supplementary Material 5. Figure S5: Differential gene expression changes and gene ontology in a glutamatergic neuron cell population in symptomatic rNLS8 mouse brain. Differential gene expression in layer 4/5 intratelencephalically projecting neurons. a Volcano plot showing significant gene expression changes. b Gene ontology analysis highlighting the most impacted pathways by significant gene upregulation or downregulation.

Source: Figshare

DOI: 10.6084/m9.figshare.31246308

Authors: Waldherr, Sarah M., Eck, Randall J., Hincks, Joshua C., Currey, Heather N., Goldberg, Matvey, McMillan, Pamela J., Saxton, Aleen D., Hulsey-Vincent, Heino J., Latimer, Caitlin S., Kraemer, Brian C., Liachko, Nicole F.

Institutions: University of Washington, Geriatric Research Education and Clinical Center

Language: English

Topic: Amyotrophic Lateral Sclerosis Research

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7127713291

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