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A case of intestinal Behçet disease in a deceased donor kidney transplantation recipient

Year: 2026

Type: article

Abstract: Behçet disease (BD) is a multisystem inflammatory disorder characterized by a chronic relapsing course.Because immunosuppressive therapy is the mainstay of BD treatment, its use in transplant recipients may attenuate typical clinical manifestations, thereby complicating diagnosis.We report a case of new-onset intestinal BD that developed in a 28-year-old man 3 years after deceased donor kidney transplantation, following an episode of cytomegalovirus colitis.The patient presented with recurrent abdominal pain, diarrhea, weight loss, and hematochezia.Colonoscopy revealed a deep, oval ulcer with well-demarcated, edematous, and nodular margins in the terminal ileum as well as healed scars near the ileocecal valve, findings consistent with intestinal BD.The patient's symptoms improved after 2 weeks of therapy with colchicine, mesalazine, and mercaptopurine.This case highlights the rare, de novo development of intestinal BD years after kidney transplantation.Intestinal BD should be considered in transplant recipients presenting with unexplained abdominal pain or diarrhea.

Source: Clinical Transplantation and Research

DOI: 10.4285/ctr.25.0100

Authors: Miran Park, Jun Su Lee, Soon Man Yoon, Ji Hye Kim, Sun Moon Kim

Institutions: Chungbuk National University, Chungbuk National University Hospital

Language: English

Topic: Ocular Diseases and Behçet’s Syndrome

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Chungbuk National University