Surveillance of central-line-associated blood stream infections (CLABSI) in intensive care units of a tertiary care center in Western India
Year: 2026
Type: article
Study design: Observational Study
Abstract: Introduction: Central-line-associated bloodstream infection (CLABSI) is the most prevalent type of healthcare-associated infection (HAI). It ranks as one of the primary contributors to both morbidity and mortality in hospitals globally. The occurrence of CLABSI is influenced by a variety of risk factors. It is essential to collect precise data on the trends of incidence rates, causes, and antimicrobial resistance patterns of central line-associated bloodstream infections (CLABSIs)in the setting to formulate empirical treatment regimens and emphasize robust infection control policy. Aims: To study the prevalence, etiology and antimicrobial susceptibility of CLABSI in adult medical and surgical ICUs in a tertiary care private hospital in Jaipur, India. Methods: This prospective observational study was conducted at the medical and surgical intensive care units for adults of Mahatma Gandhi medical college and hospital, Jaipur, Rajasthan, India from January 2023 to December 2023. The CLABSI event was identified according to the Centers for Disease Control (CDC) definition as part of the routine surveillance of HAIs. The incidence rates of CLABSI (per 1.000 central line days) were calculated. Identification and antibiotic susceptibility were determined using an automated blood-culture system. Results: (14/59; 24%). 83% (33/40) of Gram-negative isolates were resistant to carbapenem, an no isolates were resistant to colistin. Conclusion: The study revealed a disproportionately high incidence of CLABSI when compared with both developed and developing countries, with multi-drug-resistant Gram-negative bacteria being the predominant causative agents. Continuous surveillance, supported by infection control practices, e.g., hand hygiene and bundle compliance audits along with stringent antimicrobial stewardship, is vital in mitigating CLABSI.
Source: PubMed
DOI: 10.3205/dgkh000618
Language: English
Subfield: Emergency Medical Services
Field: Health Professions
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7127884358