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Virucidal efficacy of a UV-C disinfection system for semi-critical medical devices according to EN 14476

Year: 2026

Type: article

Abstract: Purpose: Semi-critical medical devices, such as flexible endoscopes in otorhinolaryngology (ORL), require high-level disinfection due to their contact with mucous membranes. UV-C systems offer a rapid, non-toxic alternative to traditional reprocessing. This study evaluates the virucidal efficacy of the D60 UV-C disinfection system according to EN 14476 standards. Materials and methods: assay. Results: /mL), corresponding to >4.0 lg reduction across all tested surfaces and virus types. Adenovirus showed the highest reduction (>4.5 lg). Conclusion: The D60 system achieved broad-spectrum virucidal efficacy within one minute, meeting EN 14476 requirements. These findings support its use for safe, rapid reprocessing of semi-critical devices in high-turnover clinical settings, with potential to improve infection control and workflow efficiency.

Source: PubMed

DOI: 10.3205/dgkh000622

Authors: Rudhart, Stefan Alexander, Eichhorn, Klaus Wolfgang Georg, Rausch, Marvin, Maas, Alexander, Knof, Maximilian, Engelhart, Steffen, Mutters, Nico T., Hoch, Stephan, Strieth, Sebastian

Institutions: University Hospital Bonn, University of Bonn, Philipps University of Marburg, Universitätsklinikum Gießen und Marburg

Language: English

Topic: Medical Device Sterilization and Disinfection

Subfield: Microbiology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7127898948

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