Recombinant factor VIIa versus placebo for spontaneous intracerebral haemorrhage within 2 h of symptom onset (FASTEST): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial
Year: 2026
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Source: The Lancet
Authors: Joseph P Broderick, Andrew M Naidech, Jordan J Elm, Kazunori Toyoda, Dar Dowlatshahi, Andrew M Demchuk, Pooja Khatri, Thorsten Steiner, Philip M Bath, Heinrich J Audebert, Achala Vagal, Sohei Yoshimura, Stephan A Mayer, Lily L Wang, Noor Sabagha, J D Mocco, Carlos Molina, Richard Aviv, Emily Stinson, Syed A Quadri, Janice Carrozzella, Thien Huynh, Anh Phan, Jonathan Beall, Iris Davis, Nobuyuki Sakai, Tsuyoshi Ohta, Michiko Yokosawa, Takayuki Hara, Navdeep Sangha, Kenichi Morita, Ming Yin Dominc Tse, Christopher D Streib, Fumio Miyashita, Yolanda Silva, Yoshinari Nagakane, Tudor Gheorghiu, Chung-Huan Sun, Teruyuki Hirano, Sven Poli, Tsuyoshi Izumo, Mayumi Fukuda-Doi, Masafumi Ihara, Masatoshi Koga, Brian Buck, Kyle B Walsh, Ilana Spokoyny, James C Grotta, Joseph Broderick, James Grotta, Andrew Naidech, Jordan Elm, Kazunori Toyoda, Andrew Demchuk, Dar Dowlatshahi, Carlos Molina, Thorsten Steiner, Philip Bath, Heinrich Audebert, Jay Mocco, Pooja Khatri, Achala Vagal, Richard Aviv, Stephan Mayer, Scott Janis, Sohei Yoshimura, Syed Quadri, Emily Stinson, Noor Sabagha, Lily Wang, Janice Carrozzella, Thien Huynh, Anh Phan, Jonathan Beall, Iris Davis, Nobuyuki Sakai, Tsuyoshi Ohta, Michiko Yokosawa, Takayuki Hara, Navdeep Sangha, Kenichi Morita, Ming Yin Dominic Tse, Christopher Streib, Fumio Miyashita, Yolanda Silva, Yoshinari Nagakane, Tudor Gheorghiu, Chung-Huan Sun, Teruyuki Hirano, Sven Poli, Tsuyoshi Izumo, Mayumi Fukuda-Doi, Masafumi Ihara, Masatoshi Koga, Brian Buck, Kyle Walsh, Ilana Spokoyny, Digvijaya Navalkele, Toshiyuki Fujinaka, Joan Marti Fabregas, William Hicks, Toshiichi Watanabe, Yusuke Yakushiji, Pere Cardona Portela, Mouhammad Jumaa, Amit Kansara, Christian Nolte, Alexandra Muccilli, Raisa Martinez, Alejandro Bustamante Rangel, Hauke Schneider, Takahiro Kuwashiro, Brett Meyer, Ashkan Shoamanesh, Laura Gioia, Elizabeth Liptrap, Pierre Borczuk, Nina Gentile, Supreet Kaur, Harish Shownkeen, Jason Mathew, Jan Purrucker, Shigeru Fujimoto, Erika Marulanda-Londono, Mustapha Ezzeddine, Fernanda Carvalho Poyraz, May Nour, Anna Khanna, Lauren Ng, Peter Panagos, Jason Appleton, Bernd Kallmuenzer, Houman Khosravani, Ramesh Grandhi, Peter Vajda, Vineeta Singh, Jay Shah, Sanjeev Sivakumar, Laura Zimmerman, Errol Gordon, Robert Jackson, Michael Brogan, Dennis Rivet, Parneet Grewal, Yousef Hannawi, Ali Mansour, Babak Jahromi, Brian Silver, Eugene Scharf, Nishita Singh, Indira Natarajan, Francisco Purroy
Institutions: University of Cincinnati, Northwestern Medicine, Medical University of South Carolina, National Cerebral and Cardiovascular Center, University of Ottawa, Ottawa Hospital Research Institute, University of Calgary, Yale University, University Hospital Heidelberg, Klinikum Frankfurt Höchst, University of Nottingham, Queen's Medical Centre, Center for Stroke Research Berlin, Charité – Universitätsmedizin Berlin, New York Medical College, Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, Universitat Autònoma de Barcelona, Vall d'Hebron Hospital Universitari, Mayo Clinic in Florida, Kobe City Medical Center General Hospital, Iwate Prefectural Central Hospital, Toranomon Hospital, Kaiser Permanente, Los Angeles Medical Center, Niigata City General Hospital, University of British Columbia, University of Minnesota, Kagoshima City Hospital, Hospital Universitari de Girona Doctor Josep Trueta, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust, Queen's Medical Center, Kyorin University, Hertie Institute for Clinical Brain Research, University of Tübingen, Gifu University, University of Alberta, Memorial Hermann, Texas Medical Center, Memorial Hermann–Texas Medical Center
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W7127630967