Artificial intelligence-assisted screening reveals high prevalence of osteoporosis in Vietnamese adults using pelvic and hip radiographs
Year: 2026
Type: article
Study design: Observational Study
Abstract: Objectives: Osteoporosis is a silent disease with low screening rates in many developing countries. This study aimed to evaluate the feasibility of using an artificial intelligence (AI)-based system to screen osteoporosis from pelvic and hip radiographs in Vietnam. Methods: We conducted a cross-sectional study at a tertiary medical center in Central Vietnam in 2023. A total of 2000 consecutive pelvic and hip radiographs from patients aged ≥ 40 years were collected. After excluding poor-quality images, 1987 radiographs were analyzed using an AI-based software designed to estimate bone mineral density (BMD) from plain radiographs and derive T-scores. Osteoporosis was defined as a T-score ≤ -2.5. Patient characteristics, radiographic findings, and risk factors for osteoporosis were analyzed. Results: Among 1987 patients (mean age 66.4 ± 15.1 years; 41.3% men), osteoporosis was identified in 872 patients (43.9%). The prevalence increased with age and was higher in women than in men (58.7% vs 22.8%, P < 0.001). Osteoporosis was associated with femoral neck (OR = 3.8, 95% CI: 2.7-5.2) and intertrochanteric fractures (OR = 7.0, 95% CI: 4.5-11.0). Patients with lower T-scores had a higher risk of hip fractures, especially those with T-scores ≤ -3.0 (OR = 11.5, 95% CI: 5.5-24.5). Conclusions: AI-based analysis of pelvic and hip radiographs is a feasible and effective tool for osteoporosis screening in Vietnam. The prevalence of osteoporosis in this hospital-based setting was high, particularly among elderly women. AI-assisted screening may offer an accessible strategy for early detection of osteoporosis in resource-limited settings.
Source: Osteoporosis and Sarcopenia
Authors: Dat Minh Nguyen, Chih-Hsing Wu, Tuan Van Nguyen, Lan T. Ho-Pham, Kim Thi Hoang Dang, Hy Van Nguyen, Sung-Yen Lin, Chung-Hwan Chen, Ta-Wei Tai
Institutions: Hue Central Hospital, National Cheng Kung University Hospital, National Cheng Kung University, University of Technology Sydney, UNSW Sydney, Tam Anh Research Institute, Pham Ngoc Thach University of Medicine, Trung tâm Nghiên cứu Y sinh, Kaohsiung Medical University, Kaohsiung Medical University Chung-Ho Memorial Hospital, National Sun Yat-sen University, National Pingtung University of Science and Technology
Language: English
Subfield: Orthopedics and Sports Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $500
OpenAlex ID: W7128002164
