Work

Development of Second-Generation Phenoxyethylpiperidines as Potent Sigma-1 Receptor Agonists with Neuroprotective Potential for Alzheimer’s Disease

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c03240

Authors: Francesco Mastropasqua, Anna Teresa Lisi, Lucie Crouzier, Gabriella Rosanna Musillo, Francesca Serena Abatematteo, Mauro Niso, Benjamin Delprat, Nicola Antonio Colabufo, Vittoria Nanna, Giuseppe Felice Mangiatordi, Pietro Delre, Tina Spalholz, Matilde Colella, Winnie Deuther-Conrad, Fulvio Loiodice, Tangui Maurice, Antonio Laghezza, Carmen Abate

Institutions: University of Bari Aldo Moro, Inserm, École Pratique des Hautes Études, Université de Montpellier, Mécanismes moléculaires dans les démences neurodégénératives, Institute of Crystallography, University of Naples Federico II, Helmholtz-Zentrum Dresden-Rossendorf

Language: English

Topic: Pharmacological Receptor Mechanisms and Effects

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: European Cooperation in Science and Technology, Consiglio Nazionale delle Ricerche, NextGenerationEU

Awards: G455327546, G6996748000, G7497598371

OpenAlex ID: W7128004082

FWCI: 5.816

Cites: 45

Cited by: 3

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