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CD4+ T and myeloid cell responses to influenza vaccine stimulation in younger and older adults

Year: 2026

Type: dataset

Abstract: A single-cell transcriptomic dataset of peripheral blood mononuclear cells (PBMC) either unstimulated or stimulated with influenza vaccine antigens. This study includes twelve older and twelve younger adults. The data objects contain all PBMC, the myeloid cells, or the CD4 T cells. Raw multiplexed sequencing data can be accessed through the United States National Institute of Health Sequence Read Archive (SRA) under BioProject PRJNA1429402.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.18484661

Authors: Oakes, Jared, Simmons, Joshua, Hager-Nochowicz, Cindy, Kirk, Leslie, Eason, Joan, Halasa, Natasha, Talbot, Keipp, Bailin, Samuel, Castilho, Jessica, Kalams, Spyros

Institution: Vanderbilt University Medical Center

Language: English

Topic: Influenza Virus Research Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7128060070

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