Treatment of angle-closure glaucoma secondary to nanophthalmos: A review of surgical strategies and novel approaches
Year: 2026
Type: article
Abstract: : Nanophthalmos presents a significant management challenge when complicated by angle-closure glaucoma, primarily due to the high risk of sight-threatening perioperative complications such as malignant glaucoma and uveal effusion syndrome. This review aims to address the key question of optimal evidence-based surgical strategies for Nanophthalmos secondary to angle-closure glaucoma (NSACG) that effectively mitigate these characteristic risks. The main contribution of this review is the proposal of a novel modular surgical approach, which selectively integrates phacoemulsification (phaco), irido-zonulo-hyaloid-vitrectomy, goniosynechialysis or Ahmed glaucoma valve implantation, and scleral windows. Grounded in the pathophysiological mechanisms underlying surgical complications, this modular framework synthesizes current evidence to provide a personalized and scientifically grounded strategy for managing this refractory glaucoma subtype.
Source: Taiwan Journal of Ophthalmology
Authors: Xiaowei Yu, Yan Gao, Yan Shi, Zhigang Fan
Institutions: Beijing Tongren Hospital, Capital Medical University
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7128045890