Enhancing immunogenic cell death by targeting the GPX4-ZP3 immune checkpoint
Year: 2026
Type: editorial
Abstract: Drugs that kill cancer cells to induce immunogenic cell death (ICD) are referred to as “ICD inducers”. Such drugs are particularly efficient for the treatment of malignant disease and hence are act...
Source: OncoImmunology
Authors: Daolin Tang, Rui Kang, Peng Liu, Guido Kroemer
Institutions: The University of Texas Southwestern Medical Center, Centre National de la Recherche Scientifique, Inserm, Université Paris Cité, Université Paris-Saclay, Institut Gustave Roussy, Sorbonne Université, Centre de Recherche des Cordeliers, Analyse moléculaire, modélisation et imagerie de la maladie cancéreuse, Assistance Publique – Hôpitaux de Paris, Hôpital Européen Georges-Pompidou
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,913
Funders: Seerave Foundation, Equipex, European Commission, Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Ministry of Science and Technology of the People's Republic of China, Fondation pour la Recherche Médicale, Ministère de l'Europe et des Affaires Étrangères, Ligue Contre le Cancer, China Scholarship Council, Institut Universitaire de France, Institut National Du Cancer, Direction Générale de l’offre de Soins, Ministère des Solidarités et de la Santé, Université de Paris, HORIZON EUROPE Framework Programme, HORIZON EUROPE European Innovation Council, HORIZON EUROPE European Research Council
Awards: G1190173965, Development of “smart” amplifiers of reactive oxygen species specific to aberrant polymorphonuclear neutrophils for treatment of inflammatory and autoimmune diseases, cancer and myeloablation., Next-generation phenotypic screening for oncological applications, G1963894250, Lung cancer prevention and interception, Biomarkers affecting the transition from cardiovascular disease to lung cancer: towards stratified interception., Gut OncoMicrobiome Signatures (GOMS) associated with cancer incidence, prognosis and prediction of treatment response., Mitochondrial copper targeting to modulate inflammatory macrophages, G434337789, G4656594441, G4707887143, Microbiota-centered interventions to solve antibiotics-induced primary resistance to immune checkpoint inhibitors, Immunogenic cell death (ICD) in the cancer-immune dialogue, Energizing the failing heart, G7041469554, G7255431040, G7562053067, G82931992, G8471630636, Université de Paris, The RUSH (retention using selective hooks) system: a chemical-genetic system for the in vivo manipulation of intercellular communication
OpenAlex ID: W7128086070