Salmonella enteritidis : a rare pathogen in a polymicrobial acute prosthetic joint infection following total hip arthroplasty treated with double debridement, antibiotics, and implant retention (DAIR)
Year: 2026
Type: article
Study design: Case Report
Abstract: Prosthetic joint infection (PJI) with Salmonella enteritidis is rare following orthopedic surgery and joint arthroplasty. This is a case of a 77-year-old female with left femoral transcervical fracture underwent total hip arthroplasty. At 2-weeks follow-up, the patient developed a PJI that was treated with double debridement, antibiotics, and implant retention (DAIR). Intraoperative cultures revealed unusual S. enteritidis without a primary focus of infection as part of polymicrobial PJI. She received a 3-month course of antibiotics including per os (PO) azithromycin and intravenous (IV) ceftriaxone that was switched to IV meropenem. At last follow-up, infection had resolved, inflammatory markers normalized, there was no evidence of prosthetic loosening and the patient was ambulatory. Salmonella organism is an atypical isolate in PJI. In the absence of a primary cause and in the context of acute infection, double DAIR is a viable option to salvage the prosthesis when a dual approach of aggressive intraoperative debridement and postoperative antibiotics coverage is employed.
Source: Journal of Surgical Case Reports
DOI: 10.1093/jscr/rjaf502
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,000
OpenAlex ID: W7128314113