Work

The Overlap of Migraine and Transient Global Amnesia: A Case Report and Literature Review on the Concept of “Migramnesia”

Year: 2026

Type: article

Abstract: Introduction: The pathophysiological relationship between migraine and transient global amnesia (TGA) remains unclear. We present a case of TGA occurring temporally with a migraine attack and review the existing literature on this potential association, sometimes termed "migramnesia." Case Presentation: A 58-year-old man with a history of episodic migraine with aura experienced a severe typical migraine headache. Approximately 3 h after onset, he awoke with profound anterograde and retrograde amnesia lasting 3 h, meeting clinical criteria for TGA. He had no recollection of the amnestic episode or the preceding headache. Brain MRI was unremarkable. Conclusion: This case adds to the limited number of reports describing a temporal link between migraine and TGA events. A review of the literature reveals conflicting evidence regarding migraine as a risk factor for TGA recurrence. While our case and some studies suggest a plausible association, the evidence is inconsistent. This case highlights the need for further research, including rigorous prospective studies and analyses of potential migraine-related subgroups within TGA populations, to clarify any underlying pathophysiological connections.

Source: Case Reports in Neurology

DOI: 10.1159/000550438

Authors: Kaveh Bahrami, Jamshid Tabeshpour, Fereydun Moradi

Institutions: Mashhad University of Medical Sciences, Islamic Azad University, Damghan Branch, Gonabad University of Medical Sciences

Language: English

Topic: Migraine and Headache Studies

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,030