Correction: Comparison of HBV-specific T cell reactivity across the pregnant, postpartum and non-pregnant women with chronic HBV infection
Year: 2026
Type: erratum
Abstract: Frontiers Media SA 3 pregnant women (pregnant group), 26 patients giving birth within six months (postpartum group), and 31 non-pregnant patients at childbearing age (non-pregnant group) using the in-houseELISpot assay to compare HBV-specific T cell reactivity across the three groups. That study concluded that pregnancy reduced HBV-specific T cell reactivity in the women with chronic HBV infection, but NUC treatment may have improved specific T-cell function.The present study commenced after July, 2023, enrolling new patients to further confirm our previous findings. Finally, 283 HBV-infected patients (129 pregnant patients, 58 postpartum patients giving birth within six months, and 96 non-pregnant patients) were tested using the inhouse ELISpot assay. This study was submitted to Frontiers in Immunology on July 9, 2024, and differs from our prior study in its conclusions: here, we found that while pregnancy can reduce HBV-specific T cell reactivity in women with chronic HBV infection, NUC treatment did not improve their HBV-specific T cell reactivity.Two independent cohorts (100 patients in the first study, and 283 patients in the present study)were enrolled in these studies. The original version of this article has been updated.
Source: Frontiers in Immunology
Authors: Genju Wang, Fangping Yue, Ziyue Zhang, Yandan Wu, Ruixue Ji, Guanlun Zhou, Ying Ji, Chuanlai Shen
Language: English
Topic: Hepatitis B Virus Studies
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W7128433541
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