Outside Back Cover: Unraveling Biomimetic Hydrogen Bonds of Dinucleotides by a Crown‐Ether‐Functionalized Tetraphenylethene‐Based Cage (Angew. Chem. Int. Ed. 11/2026)
Year: 2026
Type: article
Abstract: In the Research Article (e23981), Lin Cheng, Liping Cao, and co-workers designed and synthesized a crown-ether-functionalized tetraphenylethene-based cationic cage. This multi-cavity molecular cage establishes a multi-domain cooperative hydrophobic microenvironment that enhances hydrogen bonding among sequence-diverse dinucleotides in aqueous conditions. The study provides valuable insights into the sequence-dependent diversity of base hydrogen-bonding structures within artificial systems, potentially uncovering patterns that may also be present in nature.
Institution: Northwest University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W7128474285
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