Work

IL-4–STAT6 signaling delays protective CD8+ T cell bystander activation by antagonizing IL-18 sensing

Year: 2026

Type: article

Source: Nature Immunology

DOI: 10.1038/s41590-026-02430-9

Authors: Nicholas J. Maurice, Talia S. Dalzell, Trevor N. Tankersley, Ka Hyun Rhee, Katharine E. Block, Nicholas N. Jarjour, Taylor A. DePauw, Sarah M. Wall, Sara E. Hamilton, Stephen C. Jameson

Institutions: University of Minnesota, Medical College of Wisconsin

Language: English

Topic: T-cell and B-cell Immunology

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Institute of Allergy and Infectious Diseases

Awards: Paving the way for bystander T cell immunotherapies, Profiling and leveraging bystander T cells within the tumor microenvironment, Role of S1PRs and KLF transcription factors in CD8T cell trafficking, Understanding the functional agility of effector memory CD8 T cells, Cytokine regulation of recirculating and tissue-resident memory CD8+ T cells in homeostasis and inflammation, T Cell Homeostasis, Investigating mechanisms of bystander CD8 T cell mediated immunopathology

OpenAlex ID: W7128495250

FWCI: 2.626

Cites: 55

Cited by: 1

Related to: 10