Work

Quantification of per- and polyfluoroalkyl substances in plasma and follicular fluid of patients undergoing in vitro fertilization in Iowa: A pilot study

Year: 2026

Type: article

Abstract: Per- and polyfluoroalkyl substances (PFAS) are a class of persistent synthetic chemicals that impart oil, water, and stain repellency to products. The use of PFAS has expanded in industrial and consumer products, including cleaning, personal care, and food items. The PFAS are absorbed via the gastrointestinal tract, respiratory system, and skin, after which they accumulate in the liver through interactions with fatty acid-binding proteins. They subsequently are distributed systemically via noncovalent binding to serum albumin, facilitating their presence in tissues, such as plasma and follicular fluid.

Source: F&S Reports

DOI: 10.1016/j.xfre.2025.11.009

Authors: Prapti Singh-Herren, Samantha Good, Karen M. Summers, Joseph A. Charbonnet, Amy E. Sparks, Aileen F. Keating

Institutions: University of Iowa, University of Iowa Health Care, Iowa State University

Language: English

Topic: Per- and polyfluoroalkyl substances research

Subfield: Environmental Chemistry

Field: Environmental Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,000