Work

Seeing elephants and drinking water from a porcelain vase - A case of septin-7 antibody-associated encephalitis presenting as a severe disorganized psychosis

Year: 2026

Type: article

Study design: Case Report

Abstract: Identifying autoimmune encephalitis (AIE) in patients with predominant psychiatric symptoms poses a diagnostic challenge for psychiatrists and neurologists, especially when CSF and MRI findings are inconclusive. We report a case of septin-7 AIE presenting as steroid-responsive psychosis, whose definite diagnosis could only be made years after onset.

Source: Translational Psychiatry

DOI: 10.1038/s41398-026-03877-y

Authors: Arnim Johannes Gaebler, Friederike A. Arlt, Madeleine Scharf, Stefan Wolking, Yvonne Weber, Simone Tauber, Marieluise Kirchner, Philipp Mertins, Christian Boy, Irene Neuner, Thomas Frodl, Ludger Tebartz van Elst, Harald Prüss, Ana Novakovic

Institutions: Jülich Aachen Research Alliance, RWTH Aachen University, German Center for Neurodegenerative Diseases, Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Euroimmun Medizinische Labordiagnostika (Germany), Max Delbrück Center, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Forschungszentrum Jülich, University of Freiburg, University Medical Center Freiburg

Language: English

Topic: Autoimmune Neurological Disorders and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,290

OpenAlex ID: W7128619954

FWCI: 4.155

Cites: 16

Cited by: 1

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