Work

Optimal control pulses for Bloch-Siegert shift free NMR experiments

Year: 2026

Type: article

Abstract: Compensating frequency shift due to Bloch-Siegert shift is essential for real-time decoupling of carbon detected NMR experiments. Here we develop symmetric three-band optimal control pulses that achieve robust compensation. We observe up to 83% signal-to-noise enhancement using an Optimal Control Band-Selective Homonuclear Decoupling (O-BASHD) scheme. Systematic evaluation reveals that optimal control pulse strategies significantly outperform existing techniques for homonuclear decoupling of carbon spins, reducing experiment time up to six fold. We demonstrate the generality of the approach by successfully applying it to both liquid-state and solid-state NMR experiments on challenging samples, using instruments ranging from 600 MHz to 1.2 GHz.

Source: Journal of Magnetic Resonance

DOI: 10.1016/j.jmr.2026.108030

Authors: David Joseph, Kumar Tekwani Movellan, Stefan Becker, Loren B. Andreas, Christian Griesinger

Institution: Max Planck Institute for Multidisciplinary Sciences

Language: English

Topic: Advanced NMR Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,500

Funder: Max-Planck-Gesellschaft