Year: 2026
Type: article
Study design: Observational Study
Abstract: Psoriasis is a chronic, immune-mediated inflammatory disease that affects the skin, nails, joints, and cardiovascular system. In this study, involving 50 psoriatic patients and 28 healthy controls (patients with inguinal hernia), serum elafin levels were measured using enzyme-linked immunosorbent assay (ELISA). The results revealed significantly higher serum elafin levels in the psoriatic group compared to healthy individuals. Moreover, we observed a statistically significant positive correlation between serum elafin levels and the Psoriasis Area and Severity Index (PASI) scores. These findings indicate that elafin-a protein involved in psoriasis pathogenesis-is significantly altered in the serum of psoriatic patients and may be associated with disease severity.
DOI: 10.3390/ijms27041767
Institution: Medical University of Białystok
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,499
Awards: G1522573702, G6359950357, G7277427455
OpenAlex ID: W7128676982