Work

Poxvirus attack of antiviral defense pathways unleashes an effector-triggered NF-κB response

Year: 2026

Type: article

Source: Science

DOI: 10.1126/science.adw4937

Authors: Brenna C. Remick, Joshua Q. Mao, Andrew G. Manford, Ami D. Gutierrez-Jensen, Allon Wagner, Michael Rape, Grant McFadden, Masmudur M. Rahman, Moritz M. Gaidt, Russell E. Vance

Institutions: University of California, Berkeley, Howard Hughes Medical Institute, Arizona State University, Research Institute of Molecular Pathology, Vienna Biocenter

Language: English

Topic: NF-κB Signaling Pathways

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Boehringer Ingelheim, National Institutes of Health, National Institute of Allergy and Infectious Diseases, H2020 European Research Council, National Science Foundation Graduate Research Fellowship Program

Awards: G1890141529, Dissection of Shigella pathogenesis in vivo using a new oral infection mouse model, G9000014466, G9000141535, G9000176298, G9000232243, Functional and Structural Dissection of Inflammasome Activation, The intersection of innate and adaptive immunity to intracellular pathogens, Studies in Poxvirus Host Range Genes and Tropism, Immunology & Molecular Medicine Program Training Grant, Unravelling the mechanisms of virus host species jump, Specificity and in vivo function of the Naip/Nlrc4 inflammasomes

OpenAlex ID: W7128690938

FWCI: 5.17

Cites: 57

Cited by: 2

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