Work

Krüppel-like factor 10 promotes the progression of breast cancer by activating canonical NF-κB signaling

Year: 2026

Type: article

Abstract: experiments confirmed that KLF10 promoted breast cancer metastasis, with its expression positively correlated with p65 and negatively correlated with IκBα. Overall, our study elucidates a previously unidentified mechanism driving breast cancer progression, wherein the NF-κB signaling is drastically activated.

Source: iScience

DOI: 10.1016/j.isci.2026.115015

Authors: Xue-Wei Jiang, Jing Liu, Mei-Rong Bao, Xiao-Yan Bai, Ran Tao

Institutions: Dalian University, Dalian Medical University, Second Affiliated Hospital of Dalian Medical University

Language: English

Topic: Kruppel-like factors research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240