Work

Ion‐in‐Conjugation‐Enabled Remineralized Scaffold for Spatiotemporal Control of Infection and Bone Regeneration (Adv. Funct. Mater. 13/2026)

Year: 2026

Type: article

Abstract: Bone Regeneration In their Research Article (10.1002/adfm.202517239), Zhangqin Yuan, Jinghui He, Bin Li, Song Chen, and co-workers utilize a mineralization strategy and in situ synthesis of ion-conjugated polymers (IIC) to prepare a scaffold, achieving sequential regulation of infection control and bone regeneration. The IIC coating releases antibacterial ions (Zn2+/Ni2+), exhibiting excellent antibacterial properties by inhibiting protein synthesis and DNA replication. Meanwhile, the mineral layer releases Sr2+ that promotes bone regeneration through the PI3K-Akt signaling pathway.

Source: Advanced Functional Materials

DOI: 10.1002/adfm.74188

Authors: Jiaxu Shi, Weicheng Chen, Xiaopeng Zhao, Dachuan Liu, Kai Lu, Yahao Xu, Tingting Xia, Zhangqin Yuan, Jinghui He, Bin Li, Song Chen

Institutions: Soochow University, First Affiliated Hospital of Soochow University

Language: English

Topic: Bone Tissue Engineering Materials

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W7128701764

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