Work

Is congenital thrombotic thrombocytopenic purpura a risk factor for ischemic osteonecrosis of the hip joint (Legg-Calvé-Perthes disease)?

Year: 2026

Type: article

Abstract: Weise et al. reported on a 41-year-old patient previously diagnosed with congenital thrombotic thrombocytopenic purpura undergoing total hip replacement surgery for Perthes disease. This case raises the question whether ischemic osteonecrosis of the femoral head is another so far underrecognized comorbidity causally linked to congenital thrombotic thrombocytopenic purpura.

Source: Thrombosis Journal

DOI: 10.1186/s12959-026-00838-9

Authors: Alexander Laemmle, Bernhard Lämmle

Institutions: University of Bern, University Hospital of Bern, Johannes Gutenberg University Mainz, University Medical Center of the Johannes Gutenberg University Mainz

Language: English

Topic: Complement system in diseases

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,090