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Skin Microbiome Profiling in Patients with Primary Sjögren Disease Compared to Healthy Individuals

Year: 2026

Type: article

Study design: Observational Study

Abstract: and a marked reduction in microbial diversity in SjD patients. Beta diversity analyses revealed distinct clustering among groups. Functional prediction suggested the downregulation of metabolic pathways associated with microbial homeostasis. Our findings propose that alterations in the skin microbiota may contribute to SjD pathogenesis and serve as potential biomarkers or therapeutic targets.

Source: Journal of Microbiology and Biotechnology

DOI: 10.4014/jmb.2510.10010

Authors: Sujin Jo, Hoonhee Seo, Kyung-Ann Lee, Sukyung Kim, Md Abdur Rahim, Tapan Indrajeet Barman, Hyun-Sook Kim, Ho-Yeon Song

Institutions: Soonchunhyang University, Soonchunhyang University Hospital Seoul

Language: English

Topic: Dermatology and Skin Diseases

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Research Foundation, Soonchunhyang University, Ministry of Health and Welfare, Korea Health Industry Development Institute, National Research Foundation of Korea, Ministry of Science and ICT, South Korea

Awards: G24325090, G328607676, G5277898579, G8332343790

OpenAlex ID: W7128726891

FWCI:

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