Dietary phosphorus intake and its association with metabolic syndrome and its components: a cross-sectional analysis of the UK national diet and nutrition survey (NDNS)
Year: 2026
Type: article
Study design: Observational Study
Abstract: PURPOSE: Phosphorus plays a critical role in carbohydrate and energy metabolism, yet its relationship with metabolic health outcomes remains underexplored. This study aimed to investigate the association between dietary phosphorus intake and the prevalence of metabolic syndrome (MetS), as well as individual MetS components, using data from the UK National Diet and Nutrition Survey. METHODS: Data from adults aged 19 years and older were analyzed. Dietary phosphorus intake was assessed using four-day food diaries. MetS was defined based on established clinical criteria. Logistic regression models evaluated the association between phosphorus intake quintiles and MetS occurrence, adjusting for demographic, anthropometric, dietary, and lifestyle factors. Associations between phosphorus intake and individual MetS components were examined based on both total phosphorus intake and phosphorus density. RESULTS: Individuals in the highest phosphorus intake quintile (> 1509 mg/day) exhibited a 56% lower risk of MetS compared to those in the lowest quintile (OR = 0.44, p = 0.0004). Higher phosphorus intake was associated with a decrease of 10.4 mg/dl in triglyceride levels from quintile 1 to quintile 5 (mean ± SD: 118.6 ± 87.5 vs. 108.2 ± 61.7, p = 0.002), as well as a 2.1 mmHg reduction in diastolic blood pressure (mean ± SD: 74.6 ± 11.1 vs. 72.5 ± 10.7, p = 0.001). Additionally, modest variations in HDL cholesterol and waist circumference were observed. CONCLUSION: Higher dietary phosphorus intake was associated with a lower risk of MetS and beneficial differences in certain MetS components, supporting a potential protective role of phosphorus in metabolic health.
Source: European Journal of Nutrition
Authors: R. E. Khoury, O. Obeid, M. Malla, A. Avery, S. Welham
Institutions: University of Nottingham, American University of Beirut
Language: English
Topic: Nutritional Studies and Diet
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $2,890
OpenAlex ID: W7128732831