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The Beneficial Effect of Pumpkin Seed Oil on Metabolic and Oxidative Stress Markers in Streptozotocin Diabetic Rats Fed Low Zinc Diet

Year: 2026

Type: article

Abstract: The growing interest in foods that can be beneficial to human health has recently gained global attention. People have used pumpkin seed oil in cooking and traditional medicine since ancient times. Recent data indicated that it is used also in the pharmaceutical industry. So, this study was undertaken to evaluate the protective effect of pumpkin seed oil against oxidative damage in diabetic rats fed a low-zinc diet. Animals were equally divided into five groups: three groups were fed a sufficient-zinc diet, one non-diabetic group, and two groups diabetic rats, one untreated group and the other treated with a 5% pumpkin seed oil diet. The remaining two groups were diabetics fed a zinc-deficient diet, one non-treated and the other treated with 5% pumpkin seed oil diet. After four weeks of the treatments, fasting rats were sacrificed. Zinc deficiency led to decreased body weight (p

Source: Journal of Cellular Neuroscience and Oxidative Stress

DOI: 10.37212/jcnos.1787477

Authors: Afaf Beloucif, Zine Kechrid, Malika Hamdiken, Lazhari Tichati

Institutions: Badji Mokhtar-Annaba University, University of Guelma, Environmental Research Center

Language: English

Topic: Natural Antidiabetic Agents Studies

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: diamond

OpenAlex ID: W7128734140

FWCI:

Cites: 57

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