Non-invasive ICP monitoring when invasive systems are available in the care of acute brain injured patients: a clinical approach
Year: 2026
Type: article
Abstract: Invasive intracranial pressure (ICP) monitoring is considered the gold standard for the management of patients with an acute brain injury and at risk of developing intracranial hypertension (IH). However, invasive devices (e.g., intraparenchymal probe or external ventricular drain) are expensive, not available worldwide, and might be associated with some risks. Recently, a consensus for the monitoring and management of traumatic brain injury (TBI) patients when invasive ICP is not available (B-ICONIC) was developed. This approach is based on repeated neurological evaluation, neuroimaging, and the use of non-invasive ICP monitoring tools, such as transcranial Doppler, automated pupillometry, and ultrasound optic nerve sheath diameter measurement, to titrate interventions aiming at controlling ICP. Despite this clinical algorithm was mainly proposed for low and middle-income countries where invasive ICP is not widely implemented, a potential application of this approach may exist even in healthcare facilities where direct ICP monitoring is available. This includes patients who may have contraindications to invasive monitoring, such as coagulopathy, as well as those in whom ICP monitoring is not routinely implemented, such as individuals with post-anoxic brain injury or acute liver failure, for the reported occurrence of cerebral edema and potential risk of IH in these cases. Therefore, the aim of this manuscript is to propose the extension of the B-ICONIC algorithm to a wider population, regardless of the decision to insert an ICP sensor, and to guide their management using this multimodal approach.
Institutions: Ospedale Policlinico San Martino, IRCCS Azienda Ospedaliera Metropolitana, University of Genoa, University of Parma, Ospedale di Parma, Cleveland Clinic Lerner College of Medicine, Université Libre de Bruxelles, Erasmus Hospital, University of Washington, University of Cambridge, Universidad El Bosque, Meditech Foundation, Hospital Posadas, Universidade de São Paulo
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,079
OpenAlex ID: W7128734393
