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Joint involvement and disability in children with hemophilia: A cross-sectional study from Southern Rajasthan

Year: 2026

Type: article

Abstract: Objectives: The objective is to evaluate joint involvement and disability status among children with hemophilia in Southern Rajasthan. Material and Methods: This cross-sectional observational study was conducted at the Department of Pediatrics, RNT Medical College, Udaipur, Rajasthan. A total of 66 children with hemophilia were evaluated for joint involvement and disability status using clinical examination and medical records. Statistical significance was assessed using the Chi-square test, with P < 0.05 considered statistically significant. Results: The knee joint was the most commonly affected (75.8%, P < 0.001), followed by ankle (31.8%), shoulder (16.7%), elbow (16.7%), and hip (4.5%). Overall, 44 of 66 patients (66.7%) had documented disability, which was statistically significant ( P = 0.037). Conclusions: Knee arthropathy remains the most frequent joint manifestation in children with hemophilia in Southern Rajasthan, leading to significant disability. Early prophylaxis and comprehensive care are essential to reduce hemophilic arthropathy and disability burden.

Source: Journal of Hematology and Allied Sciences

DOI: 10.25259/jhas_57_2025

Authors: Himani Dendor, Rameshwar Lal Suman, Jai Singh, Mahendra Kumar Yadav, Jignesh Damor, Rahul Bariya

Institution: Rabindranath Tagore Medical College

Language: English

Topic: Hemophilia Treatment and Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7128744405