Work

Colpocephaly in adulthood with neuropsychiatric presentation of status epilepticus and psychosis in emergency: A rare case report

Year: 2026

Type: article

Abstract: Colpocephaly is a type of congenital ventriculomegaly characterized by enlarged occipital horns of the lateral ventricles. It is often associated with partial or complete agenesis of the corpus callosum. The diagnosis of colpocephaly is typically made in infancy. Its diagnosis in adulthood without associated clinical symptoms is infrequent and frequently confused with normal pressure hydrocephalus. However, it can be differentiated due to disproportionate posterior horn dilatation and early age of onset. We report a case of a 19-year-old female diagnosed incidentally with colpocephaly who presented to us with status epilepticus and psychotic symptoms. She improved on sodium valproate 750mg and olanzapine 10mg. To the best of our knowledge, this is the first case of colpocephaly in adulthood presenting with status epilepticus and psychosis.

Source: Future Health

DOI: 10.25259/fh_73_2025

Authors: Harshit Kumar, Anita Verma, Rika Rijal, Ankit Sinha

Institutions: All India Institute of Medical Sciences, Patna, Kathmandu University

Language: English

Topic: Fetal and Pediatric Neurological Disorders

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7128768087