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Thermally Drawn Multifunctional All‐Hydrogel Fibers for Anti‐Fibrotic and Multimodal Neural Interfaces (Adv. Mater. 9/2026)

Year: 2026

Type: article

Abstract: Multifunctional All-Hydrogel Fibers Hydrogels possess both mechanical and chemical similarity to neural tissues. Although diverse hydrogels have been synthesized for biomedical applications, integrating multiple hydrogels into compact multimaterial architectures remains challenging. In their Research Article (DOI: 10.1002/adma.202511634), Seongjun Park and co-workers identify a class of thermoplastic hydrogels and introduce the hydrogel thermal drawing process (HG-TDP), a fabrication platform that seamlessly integrates functional hydrogels into multimodal and three-dimensional neural probes. The resulting all-hydrogel fibers simultaneously allow precise neuromodulation at the fiber tip while maintaining anti-fibrotic tissue interfacing along their entire length. By bridging the materials gap between neural interfaces and biological tissues, HG-TDP establishes a foundation for the development of implantable neurotechnologies that naturally integrate with the nervous system.

Source: Advanced Materials

DOI: 10.1002/adma.72254

Authors: Changhoon Sung, Kum Seok Nam, Yeji Kim, Honey Kang, Kanghyeon Kim, Chanwoong Yoon, Somin Lee, Ain Chung, Jiheong Kang, Young‐Gyun Park, Alan Jung Park, Haider Butt, Hyunwoo Yuk, Seongjun Park

Institutions: Seoul National University, Korea Advanced Institute of Science and Technology, Khalifa University of Science and Technology, Seoul National University Hospital

Language: English

Topic: Neuroscience and Neural Engineering

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W7128769626

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