Challenging anatomy, comparable outcomes: a multicenter propensity score-matched analysis of robotic hepatectomy in posterosuperior versus anterolateral segments
Year: 2026
Type: article
Study design: Observational Study
Abstract: INTRODUCTION: Robotic liver resection has become increasingly adopted for minor hepatectomies, including lesions in the anatomically challenging posterosuperior (PS) segments. This study compares the perioperative and pathological outcomes of robotic minor resections in PS versus anterolateral (AL) segments across high-volume centers in Europe. MATERIALS AND METHODS: A multicenter database of 730 robotic liver resections performed from 2011 to 2023 in nine European institutions was reviewed. After excluding major hepatectomies, patients were analyzed in three steps: overall cohort, comparison of PS vs AL resections, and two consecutive propensity score matches. RESULTS: PS resections consistently had longer operative times, increased blood loss, and increased frequency and duration of Pringle maneuver use in all analyses. Following propensity matching, postoperative outcome measures such as overall morbidity, major complications, readmission, mortality, length of stay, and R1 rates were similar for PS and AL resections. DISCUSSION: Despite greater intraoperative complexity, robotic surgery seems to offset the technical disadvantages of PS segments to obtain postoperative and pathological results comparable to AL resections. CONCLUSION: Robotic minor liver resections in PS segments are safe and feasible when performed in experienced centers, supporting their broader adoption in advanced minimally invasive hepatobiliary surgery.
Source: HPB
Institutions: University of Rome Tor Vergata, Ospedale Generale Regionale Francesco Miulli, IRCCS Ospedale San Raffaele, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele, University of Modena and Reggio Emilia, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", Ospedale Vito Fazzi, Azienda Unità Sanitaria Locale Umbria n. 2, University of Ferrara, Fondazione Poliambulanza Istituto Ospedaliero, Inserm, Hôpitaux Universitaires de Strasbourg, Hôpital Civil, Strasbourg, Institute for Translational Medicine and Liver Disease, Centre Hospitalier Universitaire de Reims, Hôpital Robert-Debré, Vita-Salute San Raffaele University
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,100
OpenAlex ID: W7128771966
