Work

Advancing mediastinal sampling in non-metastatic lymphadenopathy

Year: 2026

Type: article

Abstract: Despite advances in PET/CT, tissue confirmation remains essential for mediastinal lymphadenopathy. EBUS-TBNA is minimally invasive but limited by cytology, particularly in benign disease and lymphoma. Emerging EBUS-guided techniques, notably transbronchial mediastinal cryobiopsy, improve diagnostic yield where tissue architecture is required. The multicenter randomized study 1 strengthens evidence for its added value, while underscoring the need for selective application and standardized, indication-specific trials.

Source: Med

DOI: 10.1016/j.medj.2026.101025

Authors: Reto Engeli, Carolin Steinack, Juergen Hetzel, Thomas Gaisl

Institutions: University Hospital Zurich, University Hospital of Basel

Language: English

Topic: Lymphadenopathy Diagnosis and Analysis

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $9,350