Work

Poster Session II A330 ANALYSIS OF ESOPHAGEAL CHARACTERISTICS IN CHILDREN WITH ESOPHAGEAL ATRESIA USING FLIP PANOMETRY

Year: 2026

Type: article

Abstract: Background Esophageal atresia (EA) is the most common congenital abnormality of the oesophagus and is associated with long-term complications including dysmotility, dysphagia, gastroesophageal reflux disease, and eosinophilic oesophagitis (EoE). Aims To assess esophageal mechanical and functional properties in children with EA and to evaluate the utility of Functional Lumen Imaging Probe (FLIP) panometry in this patient population. Methods We retrospectively analysed FLIP panometry studies performed during endoscopic follow-up in EA patients. An 8- or 16-cm balloon was selected according to patient height. Where possible, we applied the 2025 Dallas criteria for data analysis. Measurements included esophagogastric junction (EGJ) characteristics, distensibility plateau (DP), compliance over 8cm and secondary peristalsis. Results Thirty-two children with EA were included, with a median age of 7,4 years (9 months – 17 years). DP corresponded with the anastomosis in most patients, with a median DP of 14mm and a distensibility index (DI) at DP of 4,0mm^2/mmHg. Both DP and DI at DP correlated with age and height. A DP of less than 15mm was associated with food impaction, while DI at DP was correlated with both dysphagia and food impaction. Secondary peristalsis was absent in 34%, diminished in 22%, normal in 28%, disordered/impaired in 13%, and spastic in 3%. A trend towards reflux oesophagitis was observed in patients with absent or diminished peristalsis. An EGJ DI of more than 4mm^2/mmHg significantly increased esophagitis risk. Reduced esophageal compliance was found in 37,5%, but was not significantly correlated with age nor DP. EoE was correlated with reduced compliance, but not with secondary peristalsis or anastomosis characteristics. The median maximal pressure during the procedure was 70mmHg. Maximal filling volume was reached in only 41% of patients. Three infants (≤ 2 years old) with severe tracheomalacia developed mild to moderate respiratory problems during balloon filling due to external trachea compression. No other complications occurred. Conclusions FLIP panometry is feasible in children with EA from a young age and provides valuable insights into the anastomosis characteristics, esophageal anatomy and motility. Caution is warranted in infants with severe tracheomalacia. Funding Agencies None

Source: Journal of the Canadian Association of Gastroenterology

DOI: 10.1093/jcag/gwaf042.330

Authors: M Awouters, C Faure

Institution: Centre Hospitalier Universitaire Sainte-Justine

Language: English

Topic: Esophageal and GI Pathology

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,198