Solid pseudopapillary neoplasm of the pancreas
Year: 2026
Type: article
Abstract: Solid pseudopapillary neoplasm (SPN) of the pancreas is a low-grade malignant pancreatic tumor characterized by low incidence and a predilection for young female patients. It exhibits unique histological and biological features, and its diagnosis and management differ significantly from those of more common pancreatic ductal adenocarcinoma and pancreatic cystic neoplasms, or the less common pancreatic neuroendocrine neoplasms. Surgical resection yields favorable outcomes for SPN; however, a minority of patients experience recurrence and metastasis. High-risk factors for recurrence and metastasis are increasingly being identified. To incorporate recent advances in the diagnosis and management of SPN and to advance the field, this review summarizes the highest level of evidence within the discipline, incorporating clinical expert experience. The goal is to summarize diagnostic and therapeutic strategies for SPN, thereby enhancing overall clinical outcomes.
Source: Journal of Pancreatology
Authors: Zhiwen Xiao, Qiaofei Liu, Feng Yang, Gang Wang, Wei Cheng, Zipeng Lu, Tao Ma, Jiyao Sheng, Dong Wang, Hanxiang Zhan, Yong An, Yunqiang Cai, Shiwei Guo, Guangbing Li, Xiangsong Wu, Yu Wen, Bin Zhou, Bo Kong, Felix Nickel, Daisuke Hashimoto, Carl-Stephan Leonhardt, Philip C. Müller, Giovanni Marchegiani, Guopei Luo
Institutions: Fudan University Shanghai Cancer Center, Peking Union Medical College Hospital, Fudan University, Huashan Hospital, Harbin Medical University, First Affiliated Hospital of Harbin Medical University, Hunan Provincial People's Hospital, Jiangsu Province Hospital, First Affiliated Hospital Zhejiang University, Jilin University, Second Affiliated Hospital of Jilin University, Capital Medical University, Beijing Friendship Hospital, Qilu Hospital of Shandong University, The First People's Hospital of Changzhou, Sichuan University, West China Hospital of Sichuan University, Second Military Medical University, Shandong Provincial Hospital, Shanghai Jiao Tong University, XinHua Hospital, Second Xiangya Hospital of Central South University, Affiliated Hospital of Qingdao University, Heidelberg University, University Medical Center Hamburg-Eppendorf, Kansai Medical University, Medical University of Vienna, University Hospital of Basel, University of Padua
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7128808335