Work

Non‐resectable extratesticular sustentacular cell tumour treated with palliative‐intent radiation and carboplatin chemotherapy in a dog

Year: 2026

Type: article

Abstract: There is limited published information regarding the diagnosis and treatment of sustentacular cell neoplasia in dogs, and no data evaluating the use of radiation and chemotherapy for those tumours that are non‐resectable. This case report describes a 5‐year‐old, male, neutered German shepherd dog presented with a large, rapidly growing inguinal mass. Advanced imaging (computed tomography), cytology, histopathology, and immunohistochemistry led to the diagnosis of sustentacular (Sertoli) cell neoplasia. The dog underwent five daily palliative radiation treatments followed by a six‐dose carboplatin chemotherapy protocol. The primary mass was static in size for 7 months following the completion of radiation therapy and 3 months following the conclusion of chemotherapy. Progressive (presumed) metastatic lymphadenopathy was observed 1 month after discontinuing carboplatin chemotherapy. The combination of therapies utilised in this case appears to have provided temporary clinical benefit; however, further research is needed to determine the best treatment recommendations for non‐resectable sustentacular cell tumours.

Source: Veterinary Record Case Reports

DOI: 10.1002/vrc2.70363

Authors: Kathryn J. Jensen, Dah‐Renn Fu, Christopher Premanandan, Rhonda Burge

Institution: The Ohio State University

Language: English

Topic: Veterinary Oncology Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $1,480