Work

The Need for Cardiovascular Bioenergetics to Solve Problems in Heart Surgery or What Is the Term “Ischemia” About?

Year: 2026

Type: article

Abstract: The impairment of biological tissue caused by ischemia is a key area of research in both natural sciences and medical research. The utilization of oxygen in the process of tissue respiration is closely linked to mitochondrial function, i.e., the directed transfer of electrons between the enzyme complexes of the respiratory chain. The Cytochrome c oxidase, complex IV of the ETC, represents the so-called “rate-limiting step.” Kadenbach’s theory has described different activity states of this enzyme, which are crucial for the production of oxygen radicals. This mechanism is an important part of understanding ischemic damage to the heart.

Source: Clinical bioenergetics

DOI: 10.3390/clinbioenerg2010003

Author: Sebastian Vogt

Institutions: Philipps University of Marburg, Universitätsklinikum Gießen und Marburg

Language: English

Topic: Cardiac Ischemia and Reperfusion

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,207