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Evaluation of Efficacy of Bupivacaine vs Articaine for Postoperative Pain Management in Open Reduction of Fracture of Mandible- an in vivo study

Year: 2026

Type: article

Abstract: Aim: To evaluate the efficacy of 0.5% Bupivacaine and 4% Articaine when administered via inferior alveolar nerve block (IANB) in patients undergoing surgical management of mandibular fractures. Material and Method: The sample consisted of 40 participants, who required management of mandibular fractures. Results: Patients receiving Bupivacaine required rescue analgesia significantly later (10.40 h) compared to those receiving Articaine (7.30 h), with a mean difference of 3.10 h ( P < 0.001). This 42% delay in rescue analgesic requirement represents a clinically meaningful improvement in postoperative pain management, potentially reducing overall analgesic consumption and associated side effects while improving patient satisfaction scores.

Source: Journal of Pharmacy And Bioallied Sciences

DOI: 10.4103/jpbs.jpbs_1268_25

Authors: Ajay K. Pillai, Dheeraj Sharma, Neha Jain, Annant Choubey, Pushpraj Singh, Saksham Nahar

Language: English

Topic: Anesthesia and Pain Management

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $250

OpenAlex ID: W7128911052

FWCI:

Cites: 5

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