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Charge Detection Mass Spectrometry and a Glu-C/Lys-C Digestion-Based Data-Dependent Approach Suggest Mono-PEGylation of a Heterogenous Therapeutic Protein

Year: 2026

Type: article

Source: Journal of Proteome Research

DOI: 10.1021/acs.jproteome.5c00788

Authors: Zoltan Szabo, Shero Lao, Katie S. Peterson, Kristina Srzentič, Kyle P. Bowen, Amanda E. Lee, Michael W. Senko, Dietmar Reusch, Steffen Lippold, Markus Haberger

Institutions: Thermo Fisher Scientific (Switzerland), Roche (United States), Genentech

Language: English

Topic: Mass Spectrometry Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7128927848

FWCI:

Cites: 24

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