Work

Visualization of oligomerization, clustering, and density transition of intrinsically disordered proteins

Year: 2026

Type: article

Abstract: This study directly visualizes how Intrinsically Disordered Proteins form condensates, revealing a multi-step nucleation process that begins with single molecules and proceeds through intermediate clusters and density transition.

Source: National Science Review

DOI: 10.1093/nsr/nwag107

Authors: Jia-Ye Li, Yi-Hao Niu, Yi-Qin Gao, Huan Wang

Institutions: Peking University, Beijing National Laboratory for Molecular Sciences

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $2,000

Funders: National Natural Science Foundation of China, Natural Science Foundation of Beijing Municipality, Peking University

Awards: G1404872021, G1425706739, G3346015794, G7850662292

OpenAlex ID: W7128928284

FWCI: 1.939

Cites: 10

Cited by: 1

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