Year: 2026
Type: article
Study design: Case Report
Abstract: Renal cell carcinoma (RCC) is a common cancer of the urinary tract that continues to increase in incidence. With advances in imaging, RCC is being detected more frequently and at earlier stages. However, metastatic disease remains a common concern, resulting in worse prognoses. Common sites of metastases include the lungs, bone, lymph nodes, liver, brain, and adrenal glands. Bladder metastases are rare, with fewer than a hundred cases reported in the literature. Cutaneous metastases are also uncommon but have been reported. The case presented is a unique account of bilateral RCC with the development of both bladder and cutaneous metastases in the setting of prolonged survival. One treatment option for cutaneous metastases is surgical resection, as described in this case. However, based on the refractory course observed in this case, surgical resection alone may be insufficient in preventing recurrence, underscoring the need for future research investigating multimodal approaches such as combination therapy with radiation or immunotherapy. This patient went on to receive hospice care, further highlighting the relationship between metastatic disease and worsening prognoses.
Source: Cureus
Authors: Jessica L Hoffman, Chase E Green, Monica Botros, Javier Corral
Institution: Texas Tech University Health Sciences Center
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7128952625