Work

Beyond Chordoma: A Comprehensive Review of Sacral Lesions

Year: 2026

Type: article

Abstract: The sacrum is a common site for a wide range of pathological processes, including benign and malignant tumors as well as non-neoplastic conditions. Accurate diagnosis of sacral lesions remains challenging due to overlapping imaging features and the anatomical complexity of the region. This review provides a comprehensive overview of sacral lesions, with emphasis on imaging characteristics, diagnostic challenges, and clinical implications. Key imaging findings are highlighted to help narrow the differential diagnosis. While certain imaging patterns may suggest specific etiologies, image-guided biopsy is often necessary for definitive diagnosis. Familiarity with the spectrum of sacral pathologies is essential for radiologists to effectively contribute to diagnosis, patient management, and multidisciplinary care.

Source: Current Oncology

DOI: 10.3390/curroncol33020115

Authors: Leonor Garbin Savarese, Nicolas Papalexis, Mateus de Andrade Hernandes, Giancarlo Facchini, Marco Miceli, Marcello Henrique Nogueira-Barbosa

Institutions: Universidade de São Paulo, Azienda Ospedaliera G. Brotzu, Istituto Ortopedico Rizzoli

Language: English

Topic: Bone Tumor Diagnosis and Treatments

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,654