Work

Markovnikov-Selective Hydroboration of Unactivated Alkenes via MHAT under Cobalt/Photoredox Dual Catalysis

Year: 2026

Type: article

Abstract: Catalytic Markovnikov-selective hydroboration of unactivated alkenes is a powerful tool for accessing alkyl boronic esters. Here, we report Markovnikov-selective MHAT hydroboration of unactivated alkenes enabled by cobalt/photoredox dual catalysis. The reaction proceeded via radical intermediates, providing high regioselectivity with mono-, di-, and trisubstituted alkenes.

Source: Organic Letters

DOI: 10.1021/acs.orglett.6c00348

Authors: Yusuke Seino, Shintaro Dozen, Tatsuhiko Yoshino, Kosuke Higashida, Shigeki Matsunaga

Institutions: Hokkaido University, Kyoto University

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: Japan Society for the Promotion of Science

Awards: G2600525053, G2604137667, G8817725964